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Uplarafenib
$260 – $2,100
Products Details
Product Description
– Uplarafenib (B-Raf IN 10) (Compound C09) is a BRAF inhibitor with an IC50 between 50 and 100 nM. Uplarafenib shows antitumor activity[1].
Web ID
– HY-148059
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C22H21F3N4O4S
References
– [1]Yong-Liang Zhu, et al. Certain Chemical Entities, Compositions, and Methods. Patent US20130053384 A1.
CAS Number
– 1425485-87-5
Molecular Weight
– 494.49
Compound Purity
– 99.15
SMILES
– O=C(C1=C(F)C(NS(=O)(CCC)=O)=CC(F)=C1F)C2=CC=C3N=CC(N4CCOCC4)=NC3=C2
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 100 mg/mL (ultrasonic;warming;heat to 60°C)
Target
– Raf
Isoform
– BRaf
Pathway
– MAPK/ERK Pathway
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
