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Products Details
Product Description
– UNC6349 (Ket2), a diethyllysine (Ket2)-containing ligand, binds to wild-type CBX5, with a KD of 3.2 μM[1].
Web ID
– HY-142953
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C41H57N7O11
References
– [1]Kean KM, et al. Systematic Variation of Both the Aromatic Cage and Dialkyllysine via GCE-SAR Reveal Mechanistic Insights in CBX5 Reader Protein Binding. J Med Chem. 2022;65(3):2646-2655.
Molecular Weight
– 823.93
SMILES
– O=C(C1=COC=C1)NC(C(N[C@@H](C)C(N[C@@H](CC2=CC=C(C(OC)=C2)OC)C(N[C@H](C(N[C@H](C(N)=O)CO)=O)CCCCN(CC)CC)=O)=O)=O)C(C3=CC=CC=C3)O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Epigenetic Reader Domain
Pathway
– Epigenetics
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
