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Products Details
Product Description
– UNC4203 is a potent, orally available and highly selective MERTK inhibitor, with IC50s of 1.2 nM, 140 nM, 42 nM and 90 nM for MERTK, AXL, TYRO3 and FLT3, respectively[1].
Web ID
– HY-124502
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C30H44N6O
References
– [1]Hongchao Zheng, et al. UNC5293, a potent, orally available and highly MERTK-selective inhibitor. Eur J Med Chem. 2021 Aug 5;220:113534.
CAS Number
– 1818234-19-3
Molecular Weight
– 504.71
SMILES
– O[C@@H]1CC[C@H](CC1)N2C=C(C3=CN=C(N=C32)N[C@@H](C)CCC)C4=CC=C(C=C4)CN5CCN(CCC5)C
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– FLT3;TAM Receptor
Pathway
– Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
