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Umbellulone
$340 – $520
Products Details
Product Description
– Umbellulone is an active constituent of the leaves of Umbellularia californica. Umbellulone stimulates the TRPA1 channel in a subset of peptidergic, nociceptive neurons, activating the trigeminovascular system via this mechanism[1].
Web ID
– HY-135013
Storage Temperature
– -20°C, 3 years (Powder)
Shipping
– Blue Ice
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C10H14O
References
– [1]Nassini R, et al. The ‘headache tree’ via umbellulone and TRPA1 activates the trigeminovascular system. Brain. 2012 Feb;135(Pt 2):376-90.
CAS Number
– 546-78-1
Molecular Weight
– 150.22
Compound Purity
– 99.00
SMILES
– O=C1[C@@]2(C(C)C)C[C@@]2([H])C(C)=C1
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– DMSO : 250 mg/mL (ultrasonic)
Target
– TRP Channel
Pathway
– Membrane Transporter/Ion Channel;Neuronal Signaling
Product type
– Natural Products
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
