Umbellulone

$340$520

Products Details

Product Description

– Umbellulone is an active constituent of the leaves of Umbellularia californica. Umbellulone stimulates the TRPA1 channel in a subset of peptidergic, nociceptive neurons, activating the trigeminovascular system via this mechanism[1].

Web ID

– HY-135013

Storage Temperature

– -20°C, 3 years (Powder)

Shipping

– Blue Ice

Applications

– Neuroscience-Neuromodulation

Molecular Formula

– C10H14O

References

– [1]Nassini R, et al. The ‘headache tree’ via umbellulone and TRPA1 activates the trigeminovascular system. Brain. 2012 Feb;135(Pt 2):376-90.

CAS Number

– 546-78-1

Molecular Weight

– 150.22

Compound Purity

– 99.00

SMILES

– O=C1[C@@]2(C(C)C)C[C@@]2([H])C(C)=C1

Clinical Information

– No Development Reported

Research Area

– Neurological Disease

Solubility

– DMSO : 250 mg/mL (ultrasonic)

Target

– TRP Channel

Pathway

– Membrane Transporter/Ion Channel;Neuronal Signaling

Product type

– Natural Products

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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