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UMB-32
$115
Only 1000 item(s) left in stock.
Products Details
Product Description
– UMB-32, a potent, selective BRD4 inhibitor, binds BRD4 with the Kd of 550 nM, and IC50 of 637 nM. UMB-32 also shows potency against TAF1, a bromodomain-containing transcription factor[1].
Web ID
– HY-117997
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C21H23N5O
References
– [1]Michael R McKeown, et al. Biased multicomponent reactions to develop novel bromodomain inhibitors. J Med Chem. 2014 Nov 13;57(21):9019-27.
CAS Number
– 1635437-39-6
Molecular Weight
– 361.44
SMILES
– CC(C)(NC1=C(C2=CC=C(C=C2)C3=C(ON=C3C)C)N=C4N1C=CN=C4)C
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Epigenetic Reader Domain
Pathway
– Epigenetics
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
