Products Details

Product Description

– UCM-13207 (compound 21) is a selective ICMT inhibitor that ameliorates basic progeria-like features. UCM-13207 can improve the survival rate of LmnaG609G/G609G mice in the mouse premature aging model[1].

Web ID

– HY-149708

Shipping

– Room temperature

Molecular Formula

– C24H32N2O2

References

– [1]Marcos-Ramiro B et al. Isoprenylcysteine carboxylmethyltransferase-based therapy for Hutchinson–Gilford progeria syndrome[J]. ACS Central Science, 2021, 7(8): 1300-1310.

CAS Number

– 1621536-10-4

Molecular Weight

– 380.52

SMILES

– O=C(CCN(CCCCCCCC)C(C1=CC=CC=C1)=O)NC2=CC=CC=C2

Clinical Information

– No Development Reported

Research Area

– others

Solubility

– 10 mM in DMSO

Target

– ICMT

Pathway

– GPCR/G Protein

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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