Download Files:
UCB-5307
$150 – $1,350
Products Details
Product Description
– UCB-5307 is a potent TNF signaling inhibitor with a KD of 9 nM for human TNFα. UCB-5307 can penetrate the preformed hTNF/hTNFR1 complex[1].
Web ID
– HY-147045
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture and light)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C22H21N3O
References
– [1]O’Connell J, et al. Small molecules that inhibit TNF signalling by stabilising an asymmetric form of the trimer. Nat Commun. 2019 Dec 19;10(1):5795.
CAS Number
– 1515887-44-1
Molecular Weight
– 343.42
Compound Purity
– 97.37
SMILES
– OC(C1=NC2=C(N1CC3=CC(C)=CC=C3C)C=CC=C2)C4=CC=NC=C4
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– DMSO : 50 mg/mL (ultrasonic)
Target
– TNF Receptor
Isoform
– CD40
Pathway
– Apoptosis
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
