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UB-165
SKU
HY-107688-Get quote
Category Reference compound
Tags Membrane Transporter/Ion Channel;Neuronal Signaling, nAChR, Neurological Disease
Products Details
Product Description
– UB-165 is a nAChR agonist, being a full agonist of the α3β2 isoform and a partial agonist of the α4β2* isoform, with a Ki value of 0.27 nM for [3H]-nicotine binding in rat brain[1].
Web ID
– HY-107688
Shipping
– Room temperature
Molecular Formula
– C13H15ClN2
References
– [1]Sharples CG, et al. UB-165: a novel nicotinic agonist with subtype selectivity implicates the alpha4beta2* subtype in the modulation of dopamine release from rat striatal synaptosomes. J Neurosci. 2000 Apr 15;20(8):2783-91.
CAS Number
– 200432-86-6
Molecular Weight
– 234.72
SMILES
– ClC1=NC=C(C2=CCC[C@@]3([H])N[C@]2([H])CC3)C=C1
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– nAChR
Pathway
– Membrane Transporter/Ion Channel;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.