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Tyrosine kinase inhibitor
$95 – $290
Products Details
Product Description
– Tyrosine kinase inhibitor is a potent tyrosine kinase inhibitor.
Web ID
– HY-10421
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C31H31FN6O5
References
– [1]Inoue T, et al.
Two cases of gastrointestinal perforation after radiotherapy in patients receiving tyrosine kinase inhibitor for advanced renal cell carcinoma.
World J Surg Oncol. 2012 Aug 20;10(1):167.|[2]Bowen JM, et al.
Development of a rat model of oral small molecule receptor tyrosine kinase inhibitor-induced diarrhea.
Cancer Biol Ther. 2012 Nov 1;13(13).|[3]Sun FK, et al.
Multi-targeted tyrosine kinase inhibitor sunitinib: a novel strategy for sporadic malignant pheochromocytoma.
Chin Med J (Engl). 2012 Jun;125(12):2231-4.|[4]Thamm DH.
Tyrosine kinase inhibitor special issue.
Vet Comp Oncol. 2012 Sep;10(3):161-2. doi: 10.1111/j.1476-5829.2012.00339.x.|[5]Eriksson A, et al.
The novel tyrosine kinase inhibitor AKN-028 has significant antileukemic activity in cell lines and primary cultures of acute myeloid leukemia.
Blood Cancer J. 2012 Aug 3;2:e81. doi: 10.1038/bcj.2012.28.|[6]Paul MK, et al. Tyrosine kinase – Role and significance in Cancer. Int J Med Sci. 2004;1(2):101-115.
CAS Number
– 1021950-26-4
Molecular Weight
– 586.61
Compound Purity
– 99.96
SMILES
– O=C(NC1=CC=C(C=C1)F)C2(CC2)C(NC3=CC=C(C=C3)OC4=C5C(NC(C(NCCN6CCOCC6)=O)=C5)=NC=C4)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : ≥ 46 mg/mL
Target
– c-Met/HGFR
Pathway
– Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
