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Products Details
Product Description
– Tyrosinase-IN-13 (compound 3c), a derivative of Flurbiprofen (HY-10582), is a potent, non-competitive tyrosinase inhibitor (IC50=68 μM; Ki=36.3 μM). Tyrosinase-IN-13 is cytotoxic against hepatocellular carcinoma (HepG2), colorectal cancer (HT-29), and melanoma (B16F10)[1].
Web ID
– HY-155240
Shipping
– Room temperature
Molecular Formula
– C23H18ClFN4OS
References
– [1]Zengin Kurt B, et al. Synthesis of flurbiprofen thiadiazole urea derivatives and assessment of biological activities and molecular docking studies. Chem Biol Drug Des. 2023 Aug 31.. .
Molecular Weight
– 452.93
SMILES
– FC1=C(C2=CC=CC=C2)C=CC(C(C)C3=NN=C(NC(NC4=CC(Cl)=CC=C4)=O)S3)=C1
Clinical Information
– No Development Reported
Research Area
– cancer
Solubility
– 10 mM in DMSO
Target
– Tyrosinase
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
