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Products Details
Product Description
– Tubulin polymerization-IN-38 is an analogue of Tubulysin (HY-128914), a potent anticancer agent. Tubulin polymerization-IN-38 inhibits tubulin polymerization (tubulin polymerisation), thereby inducing apoptosis (apoptosis). Tubulysin series products are potent anti-microtubule toxins (anti-microtubule toxins) and can be used as ADC cytotoxins (ADC Cytotoxin) to synthesize ADCs[1].
Web ID
– HY-148193
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C31H50N4O8S
References
– [1]Jonathan A. Ellman, et al. Tubulysin d analogues. WO2009012958A2.
CAS Number
– 1005192-31-3
Molecular Weight
– 638.82
SMILES
– O=C(C1=CSC([C@H](OC(C)=O)C[C@@H](N(C([C@@H](NC([C@@H]2N(C)CCCC2)=O)[C@@H](C)CC)=O)COC(CC(C)C)=O)C(C)C)=N1)O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 100 mg/mL (ultrasonic)
Target
– ADC Cytotoxin;Microtubule/Tubulin
Pathway
– Antibody-drug Conjugate/ADC Related;Cell Cycle/DNA Damage;Cytoskeleton
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
