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Products Details
Product Description
– Tubulin polymerization-IN-31 (Compound 4c) is a tubulin polymerization inhibitor with an IC50 of 3.64 μM. Tubulin polymerization-IN-31 induces cancer cell apoptosis and shows antitumor activity[1].
Web ID
– HY-147981
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C18H13ClFN3
References
– [1]Shaheen MA, et al. 1,4,5,6,7,8-Hexahydroquinolines and 5,6,7,8-tetrahydronaphthalenes: A new class of antitumor agents targeting the colchicine binding site of tubulin. Bioorg Chem. 2020 Jun;99:103831.
CAS Number
– 2421121-79-9
Molecular Weight
– 325.77
SMILES
– N#CC1=C2CCCCC2=C(C3=C(F)C=CC=C3Cl)C(C#N)=C1N
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Apoptosis;Microtubule/Tubulin
Pathway
– Apoptosis;Cell Cycle/DNA Damage;Cytoskeleton
Product type
– Reference compound
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