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Products Details
Product Description
– Tubulin polymerization-IN-29 (compound 6g) is a potent tubulin polymerization inhibitor. Tubulin polymerization-IN-29 exhibits potent antiproliferative activity. Tubulin polymerization-IN-29 can induce HeLa cells arrest in G2/M phase[1].
Web ID
– HY-147896
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C25H20FNO6
References
– [1]Li Q, et, al. Synthesis and biological evaluation of benzofuran-based 3,4,5-trimethoxybenzamide derivatives as novel tubulin polymerization inhibitors. Bioorg Chem. 2020 Sep;102:104076.
CAS Number
– 630058-59-2
Molecular Weight
– 449.43
SMILES
– O=C(NC1=C(C(C2=CC=C(F)C=C2)=O)OC3=CC=CC=C13)C4=CC(OC)=C(OC)C(OC)=C4
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Microtubule/Tubulin
Pathway
– Cell Cycle/DNA Damage;Cytoskeleton
Product type
– Reference compound
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