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Products Details
Product Description
– Tubulin polymerization-IN-22 is a tubulin polymerization inhibitor with an IC50 of 8.1 μM. Tubulin polymerization-IN-22 arrests cell cycle at G2/M phase and induces apoptosis[1].
Web ID
– HY-147824
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C19H16O4
References
– [1]Guangcheng Wang, et al. Design, synthesis, and anticancer evaluation of benzophenone derivatives bearing naphthalene moiety as novel tubulin polymerization inhibitors. Bioorg Chem. 2020 Nov;104:104265.
CAS Number
– 2493052-22-3
Molecular Weight
– 308.33
SMILES
– O=C(C1=CC=C(OC)C(O)=C1)C2=C3C=CC=CC3=C(OC)C=C2
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Apoptosis;Microtubule/Tubulin
Pathway
– Apoptosis;Cell Cycle/DNA Damage;Cytoskeleton
Product type
– Reference compound
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