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Products Details
Product Description
– Tubulin polymerization-IN-2 is a potent anticancer agent targeting to β-tubulin with an IC50 value of 0.92 μM. Tubulin polymerization-IN-2 shows promising activity against various leukemia, non-small lung, renal, prostate, and breast cancer cell lines[1].
Web ID
– HY-143247
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C17H12F2N2O2
References
– [1]Elshemy HAH, et al. Development of potential anticancer agents and apoptotic inducers based on 4-aryl-4H chromene scaffold: Design, synthesis, biological evaluation and insight on their proliferation inhibition mechanism. Bioorg Chem. 2022 Jan;118:105475.
CAS Number
– 2873399-22-3
Molecular Weight
– 314.29
SMILES
– COC1=CC2=C(C(C(C#N)=C(O2)N)C3=CC(F)=C(C=C3)F)C=C1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Microtubule/Tubulin
Pathway
– Cell Cycle/DNA Damage;Cytoskeleton
Product type
– Reference compound
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