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Product Description
– Tubulin polymerization-IN-18 (compound 8) is a potent inhibitor of tubulin polymerization. Tubulin polymerization-IN-18 has the potential for the research of breast cancers and chemoresistant colon cancers[1].
Web ID
– HY-146376
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C25H25NO6
References
– [1]Malebari AM, et al. β-Lactams with antiproliferative and antiapoptotic activity in breast and chemoresistant colon cancer cells. Eur J Med Chem. 2020;189:112050.
CAS Number
– 1258011-23-2
Molecular Weight
– 435.47
SMILES
– COC1=CC(N2C([C@H]([C@@H]2C3=CC(O)=C(C=C3)OC)C4=CC=CC=C4)=O)=CC(OC)=C1OC
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Microtubule/Tubulin
Pathway
– Cell Cycle/DNA Damage;Cytoskeleton
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
