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Products Details
Product Description
– Tubulin polymerization-IN-17 (compound 23g) is a potent inhibitor of tubulin polymerization. Tubulin polymerization-IN-17 exhibits tubulin depolymerization and induced cell apoptosis and inhibits migration. Tubulin polymerization-IN-17 has the potential for the research of cancer diseases[1].
Web ID
– HY-146362
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C26H23NO5
References
– [1]Guo Q, et al. Ligand- and structural-based discovery of potential small molecules that target the colchicine site of tubulin for cancer treatment. Eur J Med Chem. 2020;196:112328.
CAS Number
– 2454175-89-2
Molecular Weight
– 429.46
SMILES
– COC1=CC(C(/C(C2=NC3=CC=CC=C3O2)=C/C4=CC=C(C=C4)C)=O)=CC(OC)=C1OC
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Apoptosis;Microtubule/Tubulin
Pathway
– Apoptosis;Cell Cycle/DNA Damage;Cytoskeleton
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
