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Products Details
Product Description
– Tubulin polymerization-IN-13 (Compound 4f) is a tubulin polymerization inhibitor (IC50=0.37 μM). Tubulin polymerization-IN-13 shows anti-proliferative activity against cancer cells, induces apoptosis and potential antivascular activity[1].
Web ID
– HY-146209
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C20H21NO6
References
– [1]Paola Oliva, et al. Design, synthesis, in vitro and in vivo biological evaluation of 2-amino-3-aroylbenzo[b]furan derivatives as highly potent tubulin polymerization inhibitors. Eur J Med Chem. 2020 Aug 15;200:112448.
CAS Number
– 2426665-56-5
Molecular Weight
– 371.38
SMILES
– CCOC1=CC2=C(C(C(C3=CC(OC)=C(C(OC)=C3)OC)=O)=C(O2)N)C=C1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Apoptosis;Microtubule/Tubulin
Pathway
– Apoptosis;Cell Cycle/DNA Damage;Cytoskeleton
Product type
– Reference compound
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