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Tubulin inhibitor 8

$571

Only 1000 item(s) left in stock.

Products Details

Product Description

– Tubulin inhibitor 8 (Compound 33b) is a tubulin inhibitor and a potent inhibitor of multiple cancer cell lines. Tubulin inhibitor 8 inhibits tubulin polymerization with an IC50 of 0.73 μM. Tubulin inhibitor 8 inhibits K562 cell growth with an IC50 of 14 nM[1].

Web ID

– HY-136123

Shipping

– Room temperature

Applications

– Cancer-programmed cell death

Molecular Formula

– C21H14N2O3

References

– [1]Prinz H, et al. N-benzoylated phenoxazines and phenothiazines: synthesis, antiproliferative activity, and inhibition of tubulin polymerization. J Med Chem. 2011 Jun 23;54(12):4247-63.

CAS Number

– 1309925-39-0

Molecular Weight

– 342.35

SMILES

– N#CC1=CC=C2N(C(C3=CC=C(OC)C=C3)=O)C4=C(C=CC=C4)OC2=C1

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– 10 mM in DMSO

Target

– Microtubule/Tubulin

Pathway

– Cell Cycle/DNA Damage;Cytoskeleton

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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