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Tubulin inhibitor 8
SKU
HY-136123-1mg
Category Reference compound
Tags Cancer, Cell Cycle/DNA Damage;Cytoskeleton, Microtubule/Tubulin
$571
Only 1000 item(s) left in stock.
Products Details
Product Description
– Tubulin inhibitor 8 (Compound 33b) is a tubulin inhibitor and a potent inhibitor of multiple cancer cell lines. Tubulin inhibitor 8 inhibits tubulin polymerization with an IC50 of 0.73 μM. Tubulin inhibitor 8 inhibits K562 cell growth with an IC50 of 14 nM[1].
Web ID
– HY-136123
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C21H14N2O3
References
– [1]Prinz H, et al. N-benzoylated phenoxazines and phenothiazines: synthesis, antiproliferative activity, and inhibition of tubulin polymerization. J Med Chem. 2011 Jun 23;54(12):4247-63.
CAS Number
– 1309925-39-0
Molecular Weight
– 342.35
SMILES
– N#CC1=CC=C2N(C(C3=CC=C(OC)C=C3)=O)C4=C(C=CC=C4)OC2=C1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Microtubule/Tubulin
Pathway
– Cell Cycle/DNA Damage;Cytoskeleton
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.