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Products Details
Product Description
– Tubulin inhibitor 29 (compound 3c) is a potent tubulin inhibitor with an IC50 value of 1.2 µM. Tubulin inhibitor 29 shows antiproliferative effects with an IC50 value of 7.5 µM for MCF-7 cells. Tubulin inhibitor 29 inhibits tubulin assembly and bounds in the colchicine site[1].
Web ID
– HY-147888
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C12H8F2O2S2
References
– [1]Khodyuk RGD, et al. Diaryl disulfides and thiosulfonates as combretastatin A-4 analogues: Synthesis, cytotoxicity and antitubulin activity. Bioorg Chem. 2020 Aug;101:104017.
CAS Number
– 2905-15-9
Molecular Weight
– 286.32
SMILES
– O=S(C1=CC=C(F)C=C1)(SC2=CC=C(F)C=C2)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Microtubule/Tubulin
Pathway
– Cell Cycle/DNA Damage;Cytoskeleton
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
