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Products Details
Product Description
– Tubulin inhibitor 23 is a potent Tubulin colchicine binding site inhibitor with anti-angiogenesis and anti-leukaemia activities. Tubulin inhibitor 23 inhibits tubulin polymerisation (IC50=4.8 μM) and exhibits anti-angiogenesis in Zebrafish (IC50=3.6 μM). Tubulin inhibitor 23 has the potential for the research of leukaemia[1].
Web ID
– HY-144818
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C26H23NO6S
References
– [1]Yao Y,wt al. Angiogenesis and anti-leukaemia activity of novel indole derivatives as potent colchicine binding site inhibitors. J Enzyme Inhib Med Chem. 2022 Dec;37(1):652-665.
CAS Number
– 170488-57-0
Molecular Weight
– 477.53
SMILES
– O=C(C1=CC(OC)=C(OC)C(OC)=C1)/C=C/C2=CN(S(=O)(C3=CC=CC=C3)=O)C4=C2C=CC=C4
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Apoptosis;Microtubule/Tubulin
Pathway
– Apoptosis;Cell Cycle/DNA Damage;Cytoskeleton
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
