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Products Details
Product Description
– Tubulin inhibitor 12 (Hit 9) is a novel tubulin inhibitor (IC50=25.3 μM). Tubulin inhibitor 12 shows anti-tumor activity and anti-proliferative activity[1].
Web ID
– HY-143250
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C24H20N2O
References
– [1]Wei Liu, et al. Discovery of novel tubulin inhibitors targeting the colchicine binding site via virtual screening, structural optimization and antitumor evaluation. Bioorg Chem. 2022 Jan;118:105486.
CAS Number
– 92575-00-3
Molecular Weight
– 352.43
SMILES
– CN(C(C1=CC(C2=CC=CC=C2)=NC3=CC=CC=C31)=O)CC4=CC=CC=C4
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Microtubule/Tubulin
Pathway
– Cell Cycle/DNA Damage;Cytoskeleton
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
