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TTK21

$109$1,200

Products Details

Product Description

– TTK21 is an activator of the histone acetyltransferases CBP/p300. TTK21 passes the blood–brain barrier, induces no toxicity, and reaches different parts of the brain when conjugated to glucose-based carbon nanosphere (CSP). TTK21 has beneficial implications for the brain functions of adult neurogenesis and long-term memory[1].

Web ID

– HY-116673

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– Neuroscience-Neuromodulation

Molecular Formula

– C17H15ClF3NO2

References

– [1]Chatterjee S, et al. A novel activator of CBP/p300 acetyltransferases promotes neurogenesis and extends memory duration in adult mice. J Neurosci. 2013;33(26):10698-10712.

CAS Number

– 709676-56-2

Molecular Weight

– 357.75

Compound Purity

– 99.43

SMILES

– ClC1=CC=C(C=C1C(F)(F)F)NC(C2=CC=CC=C2OCCC)=O

Clinical Information

– No Development Reported

Research Area

– Neurological Disease

Solubility

– DMSO : 100 mg/mL (ultrasonic;warming;heat to 60°C)

Target

– Histone Acetyltransferase

Isoform

– CBP/p300;TIP60

Pathway

– Epigenetics

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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