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Products Details
Product Description
– TSC26, a thiosemicarbazone, is a potent cruzipain (CZP) inhibitor with an IC50 of 175 nM, a pIC50 of 6.76 and a pKa of 6.6. TSC26 has the potential for parasitic diseases research[1].
Web ID
– HY-149073
Shipping
– Room temperature
Molecular Formula
– C13H13Cl2N5S
References
– [1]Gabriel Jasinski, et al. Design, synthesis and biological evaluation of novel thiosemicarbazones as cruzipain inhibitors. Eur J Med Chem. 2023 Apr 7;254:115345.
Molecular Weight
– 342.25
SMILES
– NC(N/N=C(C1=CC=C(C(Cl)=C1)Cl)CCN2C=CN=C2)=S
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Parasite
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
