Products Details

Product Description

– TSC24, a thiosemicarbazone, is a potent cruzipain (CZP) inhibitor with an IC50 of 2.86 nM, a pIC50 of 8.54 and a pKa of 8.6. TSC24 has the potential for parasitic diseases research[1].

Web ID

– HY-149068

Shipping

– Room temperature

Molecular Formula

– C15H20Cl2N4S

References

– [1]Gabriel Jasinski, et al. Design, synthesis and biological evaluation of novel thiosemicarbazones as cruzipain inhibitors. Eur J Med Chem. 2023 Apr 7;254:115345.

Molecular Weight

– 359.32

SMILES

– NC(N/N=C(C1=CC=C(C(Cl)=C1)Cl)CCN2CCCCC2)=S

Clinical Information

– No Development Reported

Research Area

– Infection

Solubility

– 10 mM in DMSO

Target

– Parasite

Pathway

– Anti-infection

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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