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Products Details
Product Description
– TS-IN-2 (compound 17) is a thymidylate synthase (TS) inhibitor with an IC50 of 0.81 μM. TS-IN-2 induces cancer cell apoptosis and cell cycle arrest in S phase, and also inhibit DNA synthesis, resulting in DNA damage[1].
Web ID
– HY-149849
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C18H23N3O4S
References
– [1]Syed Nazreen, et al. New Natural Eugenol Derivatives as Antiproliferative Agents: Synthesis, Biological Evaluation, and Computational Studies. ACS Omega. 2023 May 15;8(21):18811-18822.
CAS Number
– 2945983-00-4
Molecular Weight
– 377.46
SMILES
– S=C1OC(COC2=CC=C(CC=C)C=C2OC)=NN1CN3CCOCC3
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Thymidylate Synthase
Pathway
– Apoptosis
Product type
– Reference compound
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