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Products Details
Product Description
– Trypanothione synthetase-IN-4 is a L. infantum trypanothione synthetase (TryS) inhibitor, and the activity is dependent on the concentration of the polyamine substrate. Trypanothione synthetase-IN-4 has potent antileishmanicidal activity with an EC50 value of 0.6 μM and a selectivity index of 35. Trypanothione synthetase-IN-4 can be used for the research of leishmaniasis[1].
Web ID
– HY-151149
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C29H52INO2
References
– [1]M. Alcón-Calderón, et al. Identification of L. infantum trypanothione synthetase inhibitors with leishmanicidal activity from a (non-biased) in-house chemical library, European Journal of Medicinal Chemistry (2022).
Molecular Weight
– 573.63
SMILES
– C[N+](C)(CC1=CC(OC)=C(C=C1)OCCCCCCCCCCCCCC)C2CCCC2.[I-]
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Parasite
Isoform
– Leishmania
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
