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Products Details
Product Description
– TRPV4 antagonist 3 is a TRPV4 antagonist (pIC50 = 8.4).
Web ID
– HY-142620
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C20H18F4N4O3S
References
– [1]Patterson JR, et al. Design and Optimization of an Acyclic Amine Series of TRPV4 Antagonists by Electronic Modulation of Hydrogen Bond Interactions. J Med Chem. 2020 Dec 10;63(23):14867-14884.
CAS Number
– 2681273-35-6
Molecular Weight
– 470.44
SMILES
– O=S(C1=CC=C(C#N)C=C1C(F)(F)F)(NCC[C@](C)(N)COC2=CC=C(C#N)C(F)=C2)=O
Clinical Information
– No Development Reported
Research Area
– Cardiovascular Disease
Solubility
– 10 mM in DMSO
Target
– TRP Channel
Pathway
– Membrane Transporter/Ion Channel;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
