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TRPM8-IN-1
SKU
HY-108461-Get quote
Category Reference compound
Tags Membrane Transporter/Ion Channel;Neuronal Signaling, Neurological Disease, TRP Channel
Products Details
Product Description
– TRPM8-IN-1 (example 14) is an inhibitor of transient receptor potential melastatin-8 (TRPM8) channels, IC50<5 μM[1].
Web ID
– HY-108461
Shipping
– Room temperature
Molecular Formula
– C23H18F4N2O
References
– [1]Norman, et al. Preparation of substituted dihydroisoquinoline derivatives for use as TRP-M8 receptor ligands. World Intellectual Property Organization, WO2009073203 A1. 2009-06-11.
CAS Number
– 1159996-20-9
Molecular Weight
– 414.40
SMILES
– O=C(N1C(C2=CC=C(C(F)(F)F)C=C2)C3=C(C=CC=C3)CC1)NC4=CC=C(F)C=C4
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– TRP Channel
Isoform
– TRPM
Pathway
– Membrane Transporter/Ion Channel;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.