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TRPA1-IN-1
SKU
HY-142214-Get quote
Category Reference compound
Tags Membrane Transporter/Ion Channel;Neuronal Signaling, Others, TRP Channel
Products Details
Product Description
– TRPA1-IN-1 is a potent, selective, and orally bioavailable TRPA1 small molecule antagonist.
Web ID
– HY-142214
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C19H17ClN6O3
References
– [1]Terrett JA, et al. Tetrahydrofuran-Based Transient Receptor Potential Ankyrin 1 (TRPA1) Antagonists: Ligand-Based Discovery, Activity in a Rodent Asthma Model, and Mechanism-of-Action via Cryogenic Electron Microscopy. J Med Chem. 2021 Apr 8;64(7):3843-3869.
CAS Number
– 2376824-92-7
Molecular Weight
– 412.83
SMILES
– CN1C=NC2=C1C(N(C=N2)CC3=NC([C@@H]4CO[C@H](C4)C5=CC=C(C=C5)Cl)=NO3)=O
Clinical Information
– No Development Reported
Research Area
– Others
Solubility
– 10 mM in DMSO
Target
– TRP Channel
Pathway
– Membrane Transporter/Ion Channel;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.