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Troxacitabine
SKU
HY-13770-10 mg
Category Oligonucleotides
Tags Cancer, Cell Cycle/DNA Damage, Nucleoside Antimetabolite/Analog
$280 – $2,250
Products Details
Product Description
– Troxacitabine is nucleoside analog with potent anticancer activity.
Web ID
– HY-13770
Storage Temperature
– 4°C (Powder, protect from light)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C8H11N3O4
References
– [1]Kadhim SA, et al. Potent antitumor activity of a novel nucleoside analogue, BCH-4556 (beta-L-dioxolane-cytidine), in human renal cell carcinoma xenograft tumor models. Cancer Res. 1997 Nov 1;57(21):4803-10.|[2]Weitman S, et al. The new dioxolane, (-)-2′-deoxy-3′-oxacytidine (BCH-4556, troxacitabine), has activity againstpancreatic human tumor xenografts. Clin Cancer Res. 2000 Apr;6(4):1574-8.|[3]Gourdeau H, et al. Antitumor activity of troxacitabine (Troxatyl) against anthracycline-resistant human xenografts. Cancer Chemother Pharmacol. 2002 Dec;50(6):490-6.
CAS Number
– 145918-75-8
Molecular Weight
– 213.19
Compound Purity
– 97.0
SMILES
– NC1=NC(N(C=C1)[C@@H]2CO[C@H](CO)O2)=O
Clinical Information
– Phase 2
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Nucleoside Antimetabolite/Analog
Pathway
– Cell Cycle/DNA Damage
Product type
– Oligonucleotides
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.