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Products Details
Product Description
– Trk-IN-6 shows excellent in vitro potency on a panel of TRK mutants (IC50 = 0.2-0.7 nM).
Web ID
– HY-139891
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C21H21F3N6O2
References
– [1]Zhuo LS, et al. Discovery of Next-Generation Tropomyosin Receptor Kinase Inhibitors for Combating Multiple Resistance Associated with Protein Mutation. J Med Chem. 2021 Oct 28;64(20):15503-15514.
CAS Number
– 2489327-43-5
Molecular Weight
– 446.43
SMILES
– FC1=CC=C(OCC(F)F)C([C@@H](C)NC2=NC3=C(C4=CN(CCO)N=C4)C=NN3C=C2)=C1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Trk Receptor
Pathway
– Neuronal Signaling;Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
