Download Files:
Products Details
Product Description
– TRK-IN-22 (compound 11) is a TRK inhibitor. TRK-IN-22 (compound 11), a typical type I inhibitor, covers the ATP-binding pocket of TRKA[1].
Web ID
– HY-150258
Shipping
– Room temperature
Molecular Formula
– C17H14ClFN4
References
– [1]Tianxiao Wu , et al. Rational drug design to explore the structure-activity relationship (SAR) of TRK inhibitors with 2,4-diaminopyrimidine scaffold. Eur J Med Chem. 2022 Feb 15;230:114096.
Molecular Weight
– 328.77
SMILES
– FC1=CC(CNC2=C(C=NC(NC3=CC=CC=C3)=N2)Cl)=CC=C1
Clinical Information
– No Development Reported
Research Area
– Others
Solubility
– 10 mM in DMSO
Target
– Trk Receptor
Pathway
– Neuronal Signaling;Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
