Download Files:
Products Details
Product Description
– TRK-IN-14 is a potent inhibitor of TRK. Protein kinases play a critical role in the control of cell growth and differentiation and are responsible for the control of a wide variety of cellular signal transduction processes. TRK-IN-14 has the potential for the research of TRK-related diseases (extracted from patent WO2012034091A1, compound X-47)[1].
Web ID
– HY-146519
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C24H21F2N5O
References
– [1]Yi Fan, et al. Imidazo [1, 2] pyridazin compounds and compositions as trk inhibitors. Patent WO2012034091A1.
CAS Number
– 1365212-84-5
Molecular Weight
– 433.45
SMILES
– FC(C=C1)=CC=C1CNC(C2=CN=C3N2N=C(N4[C@](C5=CC(F)=CC=C5)([H])CCC4)C=C3)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Trk Receptor
Pathway
– Neuronal Signaling;Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
