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Products Details
Product Description
– Trk-IN-1 (example 9), a potent tropomyosin-related kinase (Trk) inhibitor, shows potency against TrkA (3.7 nM) and TrkB (94 nM), respectively[1].
Web ID
– HY-12327
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C24H20F3N5O3
References
– [1]Mark David Andrews, et al. Pyrrolo [2, 3 -d] pyrimidine derivatives as inhibitors of tropomyosin- related kinases. WO2012137089A1.
CAS Number
– 1402438-37-2
Molecular Weight
– 483.44
SMILES
– O=C(C1=CN=CC(NC(CC2=CC=C(C=C2)C(F)(F)F)=O)=C1)C3=CN([C@@H](C)CO)C4=NC=NC=C34
Clinical Information
– No Development Reported
Research Area
– Cancer; Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Trk Receptor
Isoform
– TrkA;TrkB
Pathway
– Neuronal Signaling;Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
