Products Details

Product Description

– Trisulfo-Cy3 Methyltetrazine is a click chemistry reagent containing an methyltetrazine group. Methyltetrazine-activated Cy3 probe reacts with TCO-containing compounds via an Inverse-Electron-Demand Diels-Alder reaction to form a stable covalent bond and does not require Cu-catalyst or elevated temperatures[1][2].

Web ID

– HY-151691

Shipping

– Room temperature

Molecular Formula

– C42H49N7O10S3

References

– [1]Cy3 Methyltetrazine. |[2]Vera F C Ferreira, et al. In Vivo Pretargeting Based on Cysteine-Selective Antibody Modification with IEDDA Bioorthogonal Handles for Click Chemistry. Bioconjug Chem. 2021 Jan 20;32(1):121-132.

CAS Number

– 1676067-48-3

Molecular Weight

– 908.07

SMILES

– O=C(CCCCCN1C2=CC=C(S(=O)(O)=O)C=C2C(C)(C)/C1=CC=CC3=[N+](CCCS(=O)(O)=O)C4=C(C3(C)C)C=C(S(=O)([O-])=O)C=C4)NCC5=CC=C(C6=NN=C(C)N=N6)C=C5

Clinical Information

– No Development Reported

Research Area

– Others

Solubility

– 10 mM in DMSO

Target

– ADC Linker

Pathway

– Antibody-drug Conjugate/ADC Related

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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