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Products Details
Product Description
– Tripolin A ((E)-Tripolin A) is a specific non-ATP competitive Aurora A kinase inhibitor, with IC50 values of 1.5 μM and 7 μM for Aurora A and Aurora B, respectively[1].
Web ID
– HY-124330
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C15H11NO3
References
– [1]Iliana A Kesisova, et al. Tripolin A, a Novel Small-Molecule Inhibitor of Aurora A Kinase, Reveals New Regulation of HURP’s Distribution on Microtubules. PLoS One. 2013;8(3):e58485.
CAS Number
– 1148118-92-6
Molecular Weight
– 253.25
SMILES
– O=C1NC2=C(C=CC=C2)/C1=CC3=CC(O)=CC=C3O
Clinical Information
– No Development Reported
Research Area
– Others
Solubility
– 10 mM in DMSO
Target
– Aurora Kinase
Pathway
– Cell Cycle/DNA Damage;Epigenetics
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
