Download Files:
Products Details
Product Description
– Trimethoprim sulfate is a bacteriostatic antibiotic and an orally active dihydrofolate reductase inhibitor. Trimethoprim sulfate is active against a wide range of Gram-positive and Gram-negative aerobic bacteria. Trimethoprim sulfate has the potential for the research of urinary tract infections, Shigellosis and Pneumocystis pneumonia. Trimethoprim sulfate can inhibit infection of Influenza A virus in chick embryo when combinated with zinc[1][2][3][4].
Web ID
– HY-B0510A
Shipping
– Room temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– C14H20N4O7S
References
– [1]Laskowska, E., et al., Trimethoprim sulfate induces heat shock proteins and protein aggregation in E. coli cells. Curr Microbiol, 2003. 47(4): p. 286-9.|[2]Xiaojian Wang, et al. A Trimethoprim sulfate Conjugate of Thiomaltose Has Enhanced Antibacterial Efficacy In Vivo. Bioconjug Chem. 2018 May 16;29(5):1729-1735.|[3]Brogden, R.N., et al., Trimethoprim sulfate: a review of its antibacterial activity, pharmacokinetics and therapeutic use in urinary tract infections. Drugs, 1982. 23(6): p. 405-30.|[4]El Habbal MH. Combination therapy of zinc and trimethoprim inhibits infection of influenza A virus in chick embryo. Virol J. 2021 Jun 3;18(1):113.
CAS Number
– 56585-33-2
Molecular Weight
– 388.40
SMILES
– NC1=NC(N)=NC=C1CC2=CC(OC)=C(OC)C(OC)=C2.O=S(O)(O)=O
Clinical Information
– Launched
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Antibiotic;Antifolate;Bacterial;Influenza Virus
Pathway
– Anti-infection;Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
