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Product Description
– Trimethoprim hydrochloride is a bacteriostatic antibiotic and an orally active dihydrofolate reductase inhibitor. Trimethoprim hydrochloride is active against a wide range of Gram-positive and Gram-negative aerobic bacteria. Trimethoprim hydrochloride has the potential for the research of urinary tract infections, Shigellosis and Pneumocystis pneumonia. Trimethoprim hydrochloride can inhibit infection of Influenza A virus in chick embryo when combinated with zinc[1][2][3][4].
Web ID
– HY-B0510B
Shipping
– Room temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– C14H19ClN4O3
References
– [1]El Habbal MH. Combination therapy of zinc and trimethoprim inhibits infection of influenza A virus in chick embryo. Virol J. 2021 Jun 3;18(1):113.|[2]Laskowska, E., et al., Trimethoprim induces heat shock proteins and protein aggregation in E. coli cells. Curr Microbiol, 2003. 47(4): p. 286-9.|[3]Brogden, R.N., et al., Trimethoprim: a review of its antibacterial activity, pharmacokinetics and therapeutic use in urinary tract infections. Drugs, 1982. 23(6): p. 405-30.|[4]Xiaojian Wang, et al. A Trimethoprim Conjugate of Thiomaltose Has Enhanced Antibacterial Efficacy In Vivo. Bioconjug Chem. 2018 May 16;29(5):1729-1735.”,”,”,”,60834-30-2″
Antibody Type
– 326.78
Antibody Isotype
– NC1=NC=C(CC2=CC(OC)=C(OC)C(OC)=C2)C(N)=N1.Cl
CAS Number
– Launched
Molecular Weight
– Infection
Compound Purity
– 10 mM in DMSO
SMILES
– Antibiotic;Antifolate;Bacterial;Influenza Virus
Research Area
– Anti-infection;Cell Cycle/DNA Damage
Solubility
– Reference compound
Features & Benefits
– http://file.medchemexpress.com/batch_PDF/HY-B0510B/Trimethoprim-hydrochloride-DataSheet-MedChemExpress.pdf
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
