Treosulfan

$70$690

Products Details

Product Description

– Treosulfan (NSC 39069) is a bifunctional alkylating agent with activity in ovarian cancer and other solid tumor types.

Web ID

– HY-16503

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– Cancer-programmed cell death

Molecular Formula

– C6H14O8S2

References

– [1]Nitsch E, et al. Synergistic cytotoxic activity of treosulfan and LY 188011 in pancreatic cancer cell lines. Anticancer Res. 2014 Apr;34(4):1779-84.|[2]Peter T, et al. Programmed erythrocyte death following in vitro Treosulfan treatment. Cell Physiol Biochem. 2015;35(4):1372-80.|[3]Sjöö F, et al. Myeloablative and immunosuppressive properties of treosulfan in mice. Exp Hematol. 2006 Jan;34(1):115-21.

CAS Number

– 299-75-2

Molecular Weight

– 278.30

Compound Purity

– 98.0

SMILES

– O[C@H]([C@@H](O)COS(C)(=O)=O)COS(C)(=O)=O

Clinical Information

– Launched

Research Area

– Cancer

Solubility

– DMSO : ≥ 100 mg/mL|H2O : 50 mg/mL (ultrasonic)

Target

– DNA Alkylator/Crosslinker

Pathway

– Cell Cycle/DNA Damage

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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