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TRAP-6-IN-1
SKU
HY-146333-Get quote
Category Reference compound
Tags Cardiovascular Disease, GPCR/G Protein, Protease Activated Receptor (PAR)
Products Details
Product Description
– TRAP-6-IN-1 (Compound 8) is a dual collagen and TRAP-6 inhibitor with IC50 values of 17.12 µM and 11.88 µM against collagen and TRAP-6, respectively. TRAP-6-IN-1 inhibits agonist-induced platelet aggregation in a non-competitive manner[1].
Web ID
– HY-146333
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C18H20O3
References
– [1]Méndez D, et al. Synthesis of antiplatelet ortho-carbonyl hydroquinones with differential action on platelet aggregation stimulated by collagen or TRAP-6. Eur J Med Chem. 2020 Apr 15;192:112187.
CAS Number
– 2068737-10-8
Molecular Weight
– 284.35
SMILES
– CCC1(CC)C=CC2=O[H]OC3=C2C1=C(C4=C3CC=CC4)O
Clinical Information
– No Development Reported
Research Area
– Cardiovascular Disease
Solubility
– 10 mM in DMSO
Target
– Protease Activated Receptor (PAR)
Pathway
– GPCR/G Protein
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.