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Products Details
Product Description
– Trans-Cevimeline (AF102A) (hydrochloride), as a trans-isomer of AF102B, is a M1 selective cholinergic agonist. Trans-Cevimeline (AF102A) (hydrochloride) can be used for the research of Alzheimer’s disease[1].
Web ID
– HY-116459
Shipping
– Room temperature
Applications
– Neuroscience-Neurodegeneration
Molecular Formula
– C10H18ClNOS
References
– [1]Fisher A, et al. (+-)-cis-2-methyl-spiro(1,3-oxathiolane-5,3′)quinuclidine, an M1 selective cholinergic agonist, attenuates cognitive dysfunctions in an animal model of Alzheimer’s disease. J Pharmacol Exp Ther. 1991;257(1):392-403.
CAS Number
– 107220-29-1
Molecular Weight
– 235.77
SMILES
– C[C@@H]1SC[C@@]2(CN3CCC2CC3)O1.[H]Cl
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– mAChR
Isoform
– mAChR1
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
