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Trans (2,3)-Dihydrotetrabenazine
SKU
HY-15793A-Get quote
Category Reference compound
Tags Drug Metabolite;Monoamine Transporter, Membrane Transporter/Ion Channel;Metabolic Enzyme/Protease, Neurological Disease
Products Details
Product Description
– Trans (2,3)-Dihydrotetrabenazine ((2R,3R,11bR)-rel-Dihydrotetrabenazine), a metabolite of Tetrabenazine, shows remarkable inhibition activity on vesicular monoamine transporter (VMAT2)[1].
Web ID
– HY-15793A
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C19H29NO3
References
– [1]Kilbourn M, et al. Binding of alpha-dihydrotetrabenazine to the vesicular monoamine transporter is stereospecific. Eur J Pharmacol. 1995 May 24;278(3):249-52.
CAS Number
– 171598-74-6
Molecular Weight
– 319.44
SMILES
– COC(C=C1CCN2C[C@H](CC(C)C)[C@@H](O)C3)=C(C=C1[C@]23[H])OC
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Drug Metabolite;Monoamine Transporter
Pathway
– Membrane Transporter/Ion Channel;Metabolic Enzyme/Protease
Product type
– Reference compound
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