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Trabedersen
$470 – $1,700
Products Details
Product Description
– Trabedersen (AP 12009) is an antisense oligodeoxynucleotide that specifically inhibits TGF-β2 (TGF-beta/Smad). Trabedersen can be used for the study of malignant brain tumors and other solid tumors overexpressing TGF-β2, such as those of the skin, pancreas and colon[1][2].
Web ID
– HY-142118
Storage Temperature
– -20°C (Powder, sealed storage, away from moisture)
Shipping
– Blue Ice
Applications
– Cancer-Kinase/protease
Molecular Formula
– C177H225N60O94P17S17
References
– [1]Luc Vallières. Trabedersen, a TGFbeta2-specific antisense oligonucleotide for the treatment of malignant gliomas and other tumors overexpressing TGFbeta2. IDrugs. 2009 Jul;12(7):445-53.|[2]Karl-Hermann Schlingensiepen, et al. Transforming growth factor-beta 2 gene silencing with trabedersen (AP 12009) in pancreatic cancer. Cancer Sci. 2011 Jun;102(6):1193-200.
CAS Number
– 925681-61-4
Molecular Weight
– 5768.70
Compound Purity
– 92.09
SMILES
– [Trabedersen]
Clinical Information
– Phase 3
Research Area
– Cancer
Solubility
– H2O : 100 mg/mL (ultrasonic)
Target
– TGF-beta/Smad
Pathway
– Stem Cell/Wnt;TGF-beta/Smad
Product type
– Oligonucleotides
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
