Products Details

Product Description

– TRβ agonist 3 (Compound 3) is a potent agonist of TRβ. TRβ agonist 3 reduces lipid accumulation in HepG2 and promote lipolysis with comparable effects. TRβ agonist 3 is a new potential TRβ-selective thyromimetics[1].

Web ID

– HY-147501

Shipping

– Room temperature

Applications

– Metabolism-sugar/lipid metabolism

Molecular Formula

– C20H25NO3

References

– [1]Runfola M, et al. Design, synthesis and biological evaluation of novel TRβ selective agonists sustained by ADME-toxicity analysis. Eur J Med Chem. 2020 Feb 15;188:112006.

CAS Number

– 2411099-46-0

Molecular Weight

– 327.42

SMILES

– CC1=CC(OCC(O)=O)=CC(C)=C1CC2=CC(C(C)C)=C(C=C2)N

Clinical Information

– No Development Reported

Research Area

– Metabolic Disease

Solubility

– 10 mM in DMSO

Target

– Thyroid Hormone Receptor

Pathway

– Vitamin D Related/Nuclear Receptor

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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