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Products Details
Product Description
– TPT-004 is a TPH inhibitor. TPT-004 has superior pharmacokinetic and pharmacodynamic properties. TPT-004 also has good efficacy in preclinical models of peripheral serotonin attenuation and colorectal tumor growth[1].
Web ID
– HY-157014
Shipping
– Room temperature
Molecular Formula
– C18H20N6O3S
References
– [1]Specker E, et al. Structure-Based Design of Xanthine-Imidazopyridines and -Imidazothiazoles as Highly Potent and In Vivo Efficacious Tryptophan Hydroxylase Inhibitors. J Med Chem. 2023 Oct 31.
Molecular Weight
– 400.45
SMILES
– CCN1C2=C(C(NC1=O)=O)N(C(CC3=CN4C=C(SC4=N3)C)=N2)CC5COC5
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Tryptophan Hydroxylase
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
