Download Files:
Products Details
Product Description
– TPI-287, a blood-brain barrier-permeable microtubule stabilizer, can significantly reduce metastatic colonization of breast cancer in the brain[1].
Web ID
– HY-126899
Shipping
– Room temperature
Molecular Formula
– C46H63NO15
References
– [1]Daniel P Fitzgerald, et al. TPI-287, a new taxane family member, reduces the brain metastatic colonization of breast cancer cells. Mol Cancer Ther. 2012 Sep;11(9):1959-67.
CAS Number
– 849213-15-6
Molecular Weight
– 869.99
SMILES
– CC1(C)[C@@]2(O)C[C@H](OC([C@H](O)[C@@H](NC(OC(C)(C)C)=O)CC(C)C)=O)C(C)=C1[C@]([H])(OC(C)=O)[C@@]3([H])[C@@]4(C)[C@]([C@@](CO5)(OC(C)=O)[C@@]5([H])C[C@]4([H])OC(C=C)O3)([H])[C@@H]2OC(C6=CC=CC=C6)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Microtubule/Tubulin
Pathway
– Cell Cycle/DNA Damage;Cytoskeleton
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
