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Products Details
Product Description
– TPI-287, a blood-brain barrier-permeable microtubule stabilizer, can significantly reduce metastatic colonization of breast cancer in the brain[1].
Web ID
– HY-126899
Shipping
– Room temperature
Molecular Formula
– C46H63NO15
References
– [1]Daniel P Fitzgerald, et al. TPI-287, a new taxane family member, reduces the brain metastatic colonization of breast cancer cells. Mol Cancer Ther. 2012 Sep;11(9):1959-67.
CAS Number
– 849213-15-6
Molecular Weight
– 869.99
SMILES
– CC1(C)[C@@]2(O)C[C@H](OC([C@H](O)[C@@H](NC(OC(C)(C)C)=O)CC(C)C)=O)C(C)=C1[C@]([H])(OC(C)=O)[C@@]3([H])[C@@]4(C)[C@]([C@@](CO5)(OC(C)=O)[C@@]5([H])C[C@]4([H])OC(C=C)O3)([H])[C@@H]2OC(C6=CC=CC=C6)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Microtubule/Tubulin
Pathway
– Cell Cycle/DNA Damage;Cytoskeleton
Product type
– Reference compound
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