Download Files:
Products Details
Product Description
– TP0586352 is a LpxC inhibitor that is effective against carbapenem-resistant Klebsiella pneumoniae and does not pose a cardiovascular risk. TP0586352 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Web ID
– HY-142619
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C26H31N5O3
References
– [1]Ushiyama F, et al. Lead optimization of 2-hydroxymethyl imidazoles as non-hydroxamate LpxC inhibitors: Discovery of TP0586532. Bioorg Med Chem. 2021 Jan 15;30:115964.
CAS Number
– 2427626-11-5
Molecular Weight
– 461.56
SMILES
– NC[C@@H](N1C([C@@H](O)C)=NC=C1)C2=NOC(C(C=C3)=CC=C3C#C[C@H]4[C@@]5([H])[C@]4([H])CN(C5)C[C@@H](O)C)=C2
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Bacterial
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
