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Products Details
Product Description
– TP-6076 is a fully synthetic fluorocycline antibiotic, acts function via binding to the 30S ribosomal subunit and maintains its activity. TP-6076 displays potent mechanism-based antitranslational activity (Tet protein, IC50=0.18 μg/mL), shows a wide range of antimicrobial and antiparasitic activities[1][2].
Web ID
– HY-148182
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C28H32F3N3O7
References
– [1]Rusu A, et al. The Development of Third-Generation Tetracycline Antibiotics and New Perspectives. Pharmaceutics. 2021 Dec 5;13(12):2085. |[2]Grossman TH, et al. Fluorocycline TP-271 Is Potent against Complicated Community-Acquired Bacterial Pneumonia Pathogens. mSphere. 2017 Feb 22;2(1):e00004-17.
CAS Number
– 1575495-01-0
Molecular Weight
– 579.56
SMILES
– O[C@]12[C@](C[C@@]3([H])C(C(C4=C(O)C=C([C@]5([H])CCCN5)C(C(F)(F)F)=C4C3)=O)=C2O)([H])[C@@H](C(O)=C(C1=O)C(N)=O)N(CC)CC
Clinical Information
– Phase 1
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Antibiotic;Bacterial;Parasite
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
