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Products Details
Product Description
– TP-051 is a potent FFAR1 agonist with an Ki value of 16 nM for human FFAR1. TP-051 can increase insulin secretion in rat insulinoma cells. TP-051 can be used to research type 2 diabetes[1].
Web ID
– HY-148235
Shipping
– Room temperature
Molecular Formula
– C29H31FO6S
References
– [1]Mikami S, et al. Discovery of phenylpropanoic acid derivatives containing polar functionalities as potent and orally bioavailable G protein-coupled receptor 40 agonists for the treatment of type 2 diabetes. J Med Chem. 2012 Apr 26;55(8):3756-76.
CAS Number
– 858097-86-6
Molecular Weight
– 526.62
SMILES
– O=C(CCC1=CC=C(C=C1F)OCC2=CC=CC(C3=C(C)C=C(C=C3C)OC4CCS(=O)(CC4)=O)=C2)O
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease
Solubility
– 10 mM in DMSO
Target
– Free Fatty Acid Receptor
Pathway
– GPCR/G Protein
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
